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Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
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Serum glycylproline p-nitroanilidase activity in blood cancers

K Fujita, M Hirano, K Tokunaga

    Clinica Chimica Acta; International Journal of Clinical Chemistry
    |December 1, 1977
    PubMed

    Abstract:

    Glycylproline p-nitroanilidase activity in serum of patients with acute lymphatic leukemia, lymphosarcoma and Hodgkin's disease, and of normal neonates (umbilical blood) was significantly lower than that of normal adult controls. In contrast, the enzyme activity of patients with myelocytic leukemias did not differ significantly from that of normal controls.

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