Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cold-insoluble globulin (CIg), a circulating cell surface protein.

M W Mosesson

    Thrombosis and Haemostasis
    |December 15, 1977
    PubMed
    Summary

    The discovery and characterization of cold-insoluble globulin (CIg) in plasma are reviewed. Its structure and function in plasma, tissues, and on cell surfaces are examined.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evidence for covalent linkage between some plasma α2-antiplasmin molecules and Aα chains of circulating fibrinogen.

    Journal of thrombosis and haemostasis : JTH·2013
    Same author

    Short by one mechanism: a rebuttal.

    Journal of thrombosis and haemostasis : JTH·2010
    Same author

    Human fibrinogen heterogeneities: determination of the major Aalpha chain derivatives in blood.

    Thrombosis research·2010
    Same author

    Thrombosis risk modification in transgenic mice containing the human fibrinogen thrombin-binding gamma' chain sequence.

    Journal of thrombosis and haemostasis : JTH·2008
    Same author

    Evidence that alpha2-antiplasmin becomes covalently ligated to plasma fibrinogen in the circulation: a new role for plasma factor XIII in fibrinolysis regulation.

    Journal of thrombosis and haemostasis : JTH·2008
    Same author

    Changes in fibrinogen and fibrin induced by a peptide analog of fibrinogen gamma365-380.

    Journal of thrombosis and haemostasis : JTH·2007

    Area of Science:

    • Biochemistry
    • Hematology
    • Cell Biology

    Background:

    • Cold-insoluble globulin (CIg) is a key plasma protein with diverse biological roles.
    • Understanding CIg's historical discovery and evolving characterization is crucial for appreciating its significance.

    Purpose of the Study:

    • To provide a comprehensive review of the discovery and characterization of cold-insoluble globulin (CIg).
    • To examine the progression of knowledge regarding CIg's structure and function.
    • To explore CIg's roles in plasma, tissues, and on cell surfaces.

    Main Methods:

    • Literature review of historical scientific publications.
    • Analysis of research detailing the structural and functional properties of CIg.
    • Synthesis of findings on CIg's localization and interactions.

    Main Results:

    • The historical trajectory of CIg discovery and its initial characterization.
    • Elucidation of CIg's complex molecular structure.
    • Detailed examination of CIg's multifaceted functions in various biological contexts.

    Conclusions:

    • CIg is a historically significant protein with a well-documented discovery and characterization.
    • Knowledge of CIg's structure and function has expanded considerably over time.
    • CIg plays vital roles in plasma, tissue homeostasis, and cell-surface interactions.

    Related Experiment Videos