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Related Experiment Videos

Contraceptive efficacy determination by postcoital testing.

H Brehm, I Albrecht

    Fertility and Sterility
    |February 1, 1978
    PubMed
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    A novel vaginal contraceptive effectively immobilizes sperm and prevents cervical entry without hormonal side effects. This new method offers easy application and highly reliable protection against conception.

    Area of Science:

    • Reproductive Health
    • Contraception
    • Gynecology

    Background:

    • Hormonal contraceptives carry potential physiological risks.
    • There is a need for non-hormonal, easy-to-use contraceptive methods.
    • Vaginal delivery of spermicides presents an alternative approach.

    Purpose of the Study:

    • To evaluate the in vivo efficacy of a new vaginal contraceptive.
    • To assess its ability to immobilize spermatozoa.
    • To determine its effectiveness in preventing sperm from entering the cervical canal.

    Main Methods:

    • Direct in vivo testing of the new contraceptive device.
    • Sperm analysis in vaginal, cervical os, and cervical canal samples post-coitus.
    • Comparison with a control contraceptive agent.

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    Main Results:

    • No motile spermatozoa were found in any tested samples (vagina, cervical os, cervical canal) immediately after intercourse with the new agent.
    • No spermatozoa, even immotile, were observed in the cervical canal.
    • Control group showed motile sperm in the cervical canal in 9 out of 30 cases.

    Conclusions:

    • The new vaginal contraceptive is highly effective in immobilizing sperm and preventing their cervical canal entry.
    • It demonstrates superior efficacy compared to a control contraceptive agent.
    • This method offers a safe and effective non-hormonal option for conception prevention.