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Related Experiment Videos

Complete heart block with hyperthyroidism.

S A Eraker, R Wickamasekaran, S Goldman

    JAMA
    |April 21, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Thyrotoxicosis, or excess thyroid hormone, can cause heart block. This case shows varying heart block degrees due to Graves

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    Area of Science:

    • Cardiology
    • Endocrinology
    • Thyroid Disorders

    Background:

    • Thyroid hormone therapy is standard for hypothyroidism.
    • Thyrotoxicosis can arise from exogenous sources or endogenous overproduction.

    Observation:

    • A patient on thyroid hormone replacement developed thyrotoxicosis.
    • The patient exhibited progressive heart block, starting with Mobitz type 1 second-degree, then third-degree, and finally first-degree block.

    Findings:

    • Hyperthyroxinemia, resulting from both Graves' disease and exogenous thyroid hormone, was identified as the cause.
    • The varying degrees of heart block correlated with the severity of hyperthyroxinemia.

    Implications:

    • This case highlights the potential cardiac complications of iatrogenic or endogenous thyrotoxicosis.
  • Monitoring cardiac function is crucial in patients with thyroid dysfunction or those undergoing thyroid hormone therapy.