Acinous cell carcinoma of the larynx

Adenocarcinomas of the larynx are an unusual type of lesion that arise in the minor salivary glands. An acinous cell carcinoma that arose in a supraglottic minor salivary gland closely resembled an oncocytic adenocarcinoma on light microscopy; but on electron microscopy, the neoplasm clearly was serous in origin. Contrary to the behavior of most acinous cell carcinomas, but similar to the majority of laryngeal adenocarcinomas, the neoplasm herein discussed was extremely aggressive and developed widespread metastases, which led to the patient's death.