[Alpha-fetoprotein and cystic fibrosis (author's transl)]

Recently significantly raised serum levels of alpha-fetoprotein (AFP) were demonstrated in patients with cystic fibrosis (CF) and in their parents and some siblings; thereupon the determination of AFP was recommended for detecting heterozygote carriers of the CF-gene. These results could not be confirmed by our own investigations also using a radioimmunassay.