Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experimental streptococcal endocarditis. The early vegetation.

J Carrizosa, K Kaye, W Kobasa

    Archives of Pathology & Laboratory Medicine
    |October 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [COVID-19: Practice and ethics of videoconsultation assessment of children with autism spectrum disorder].

    Ethique & sante·2021
    Same author

    Elective, Non-urgent Procedures and Aesthetic Surgery in the Wake of SARS-COVID-19: Considerations Regarding Safety, Feasibility and Impact on Clinical Management.

    Aesthetic plastic surgery·2020
    Same author

    Histological case-control study of peeling-induced skin changes by different peeling agents in surgically subcutaneous undermined skin flaps in facelift patients.

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2017
    Same author

    First case of vaccine-strain varicella infection as manifestation of HIV in healthcare worker: a case report and review of the literature.

    The Journal of hospital infection·2017
    Same author

    Near Infrared Spectroscopy (NIRS) for the determination of the milk fat fatty acid profile of goats.

    Food chemistry·2015
    Same author

    [Cognitive remediation therapy for children: literature data and clinical application in a child and adolescent psychiatry department].

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2015
    Same journal

    Assessing Human Epidermal Growth Factor Receptor 2 in Urothelial Carcinoma: Insights From Clinical Practice Into Scoring Criteria, Histologic Subtypes, and Genomic Characteristics Across Disease Sites.

    Archives of pathology & laboratory medicine·2026
    Same journal

    Cross-Reactivity of TPIT Antibody Clone OTI2G1 in Chordoma: Structural Mechanisms and Diagnostic Implications.

    Archives of pathology & laboratory medicine·2026
    Same journal

    Paracoccidioidomycosis at Autopsy: A Case Series and Literature Review.

    Archives of pathology & laboratory medicine·2026
    Same journal

    Accuracy of Cytology Diagnosis for Well Differentiated Neuroendocrine Tumors: Assessment by the College of American Pathologists Non-Gynecologic Slide Program.

    Archives of pathology & laboratory medicine·2026
    Same journal

    Serum Immunofixation Electrophoresis Guidance Conflict: A Call to Harmonize.

    Archives of pathology & laboratory medicine·2026
    Same journal

    In Reply.

    Archives of pathology & laboratory medicine·2026
    See all related articles

    This study shows that Streptococcus mitis bacteria colonize aortic valve vegetation internally, forming microcolonies and later large colonies within 24 hours. The vegetation surface, despite appearing smooth, is rough and irregular, facilitating bacterial adhesion and growth.

    Area of Science:

    • Cardiovascular Pathology
    • Microbiology
    • Electron Microscopy

    Background:

    • Aortic valve vegetation can lead to serious complications.
    • Understanding the interaction between bacteria and vegetation is crucial for treatment.

    Purpose of the Study:

    • To investigate the dynamic changes within aortic valve vegetation after Streptococcus mitis infection.
    • To characterize the surface morphology of vegetation using scanning electron microscopy.

    Main Methods:

    • Studied rabbit aortic valve vegetation before and after intravenous injection of Streptococcus mitis.
    • Utilized light and scanning electron microscopy to examine vegetation structure and bacterial colonization.

    Main Results:

    • Uninfected vegetation showed smooth edges but irregular surfaces with leukocytes.

    Related Experiment Videos

  • Following S. mitis injection, leukocytes infiltrated vegetation edges.
  • Bacteria were observed as microcolonies at 6 hours and large colonies at 24 hours, primarily within the vegetation.

    • Conclusions:

    • Streptococcus mitis preferentially colonizes the interior of aortic valve vegetation.
    • The irregular surface of vegetation aids bacterial adherence and colonization.
    • Early bacterial presence within vegetation is key to understanding infective endocarditis progression.