Related Experiment Videos
The Arias-Stella reaction revisited.
Archives of Pathology & Laboratory Medicine
|December 1, 1978
Summary
The Arias-Stella reaction, a change in the endometrium, was found in normal early pregnancies. This indicates it is a natural response to a developing embryo.
Area of Science:
- Reproductive biology
- Histopathology
- Human embryology
Background:
- The Arias-Stella reaction is a cytologic change observed in the endometrium.
- Its precise role in normal early pregnancy is not fully understood.
Purpose of the Study:
- To investigate the occurrence and significance of the Arias-Stella reaction in normal human gestational endometrium.
Main Methods:
- Histopathological examination of endometrial samples from the Hertig collection at the Carnegie Institute.
- Correlation of Arias-Stella reaction presence with estimated embryonic age.
Main Results:
- The Arias-Stella reaction was identified in five cases of normal human gestational endometrium.
- The earliest observed case was associated with an ovum estimated to be 17 days old.
Conclusions:
- The Arias-Stella reaction appears to be a physiologic endometrial response to viable trophoblastic tissue.
- This finding supports the interpretation of the Arias-Stella reaction as a normal gestational phenomenon.