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[Synthesis and virostatic activity of adamantan-1-carbonic acid amidines (author's transl)]
Arzneimittel-Forschung
|January 1, 1978
Abstract:
33 different adamntyl amidines containing four different structural types were synthesized and checked for virostatic activity. The activity of compounds of type II seems to originate in their ability to form H-bonds. The strength of antiviral activity is at least partly determined by the electronic effects of substituents at the benzene ring.