Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comparative cranial CT enhancement in the normal primate.

B P Drayer, S K Wolfson, A E Rosenbaum

    Investigative Radiology
    |January 1, 1979
    PubMed
    Summary

    This study evaluated intravenous, intrathecal, and inhalation CT enhancement techniques in baboons. Intrathecal metrizamide and inhalation xenon methods showed promise for visualizing primate neurovasculature and assessing cerebral blood flow.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Calciphylaxis in uraemic and nonuraemic settings: clinical risk factors and histopathological findings.

    Clinical and experimental dermatology·2021
    Same author

    A role for coding functional variants in HNF4A in type 2 diabetes susceptibility.

    Diabetologia·2010
    Same author

    Secondary intraocular lenses in eyes with aphakia or dislocated IOL: impact of suture fixation on early and late complications.

    Klinische Monatsblatter fur Augenheilkunde·2008
    Same author

    Genome scan of schizophrenia families in a large Veterans Affairs Cooperative Study sample: evidence for linkage to 18p11.32 and for racial heterogeneity on chromosomes 6 and 14.

    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics·2005
    Same author

    Toxic effects of indocyanine green, infracyanine green, and trypan blue on the human retinal pigmented epithelium.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2005
    Same author

    Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects.

    Diabetologia·2004

    Area of Science:

    • Comparative anatomy
    • Radiology
    • Primate neuroimaging

    Background:

    • Computed tomography (CT) is crucial for neuroimaging.
    • Evaluating nonhuman primate brains aids human neurological research.
    • Developing advanced CT enhancement techniques is essential for detailed anatomical and functional studies.

    Purpose of the Study:

    • To describe and evaluate intravenous, intrathecal, and inhalation contrast enhancement techniques for CT scans in baboons (Papio cynocephalus/anubis).
    • To assess the efficacy of these methods in visualizing specific cerebral structures and measuring regional cerebral blood flow.

    Main Methods:

    • Intravenous contrast administration for vascular enhancement.
    • Intrathecal contrast administration (air and metrizamide) for cerebrospinal fluid spaces.

    Related Experiment Videos

  • Inhalation of xenon gas for brain perfusion imaging.
  • Repeated CT scans during xenon clearance for blood flow analysis.

    • Main Results:

    • Intravenous enhancement clearly defined the falx cerebri, cortical vasculature, vein of Galen, straight sinus, and tentorium cerebelli.
    • Intrathecal air caused distortion; metrizamide provided accurate delineation of subarachnoid spaces with minimal adverse effects.
    • Inhalation xenon resulted in symmetrical brain enhancement, correlating with blood xenon concentration.
    • Xenon clearance analysis allowed for approximate regional cerebral blood flow assessment.

    Conclusions:

    • Intravenous and intrathecal metrizamide CT enhancement are effective for baboon neuroanatomy.
    • Inhalation xenon CT enhancement provides valuable data on brain perfusion and regional cerebral blood flow in primates.
    • These techniques enhance the utility of CT for nonhuman primate neuroimaging research.