[2-(Diethylamino)pyrimidines 2nd Communication: Analgesics (author's transl)]

By condensation of 1,1-diethylguanidine (1) with beta-diketones (2), the 2-(diethylamino)pyrimidines (3) are formed. Aside from beta-diketones substituted by aliphatic (2 a--e), mixed aliphatic-aromatic (2f), and pure aromatic-carbocyclic (2g and h) moieties, also those carrying aromatic-heterocyclic (2i and 4) substitutents are amenable to this reaction.