Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Progressive combined amyloid-elastic stain.

P Leung, T J Muckle

    Archives of Pathology
    |November 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    A new progressive staining method allows simultaneous visualization of elastic fibers and amyloid deposits in both animal and human tissues. This technique is effective for various types of amyloidosis, enhancing diagnostic capabilities.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Exercise is Medicine® Canada on Campus Casebook: Evaluation of a novel knowledge translation tool and lessons learned.

    Evaluation and program planning·2021
    Same author

    Open versus laparoscopic appendicectomy in acute appendicitis: results of a district general hospital.

    South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2018
    Same author

    Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells.

    Clinical and experimental immunology·2014
    Same author

    Systematic review and meta-analysis of published trials comparing the effectiveness of transanal endoscopic microsurgery and radical resection in the management of early rectal cancer.

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2013
    Same author

    Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis.

    Clinical and experimental immunology·2013
    Same author

    High-damage-threshold static laser beam shaping using optically patterned liquid-crystal devices.

    Optics letters·2011
    See all related articles

    Area of Science:

    • Histopathology
    • Biochemistry
    • Medical Diagnostics

    Background:

    • Elastic structures and amyloid deposits are key histological features in various diseases.
    • Current staining methods often require separate procedures, limiting simultaneous analysis.
    • Accurate identification of both components is crucial for disease diagnosis and research.

    Purpose of the Study:

    • To develop a novel, progressive staining technique.
    • To enable the simultaneous demonstration of elastic structures and amyloid deposits within a single tissue section.
    • To validate the technique's efficacy across different tissue types and amyloidosis classifications.

    Main Methods:

    • A progressive staining protocol was developed and optimized.
    • The technique was applied to both animal and human tissue samples.

    Related Experiment Videos

  • Stained sections were evaluated for the clear depiction of elastic fibers and amyloid.

    • Main Results:

    • The progressive staining technique successfully demonstrated elastic structures and amyloid deposits concurrently in the same section.
    • The method proved effective for both animal and human tissues.
    • Both pericollagen and perirecticulin types of amyloidosis were amenable to this staining approach.

    Conclusions:

    • A versatile and efficient staining method for simultaneous visualization of elastic and amyloid components has been established.
    • This technique offers a valuable tool for histopathological diagnosis and research, particularly in conditions involving both elastic tissue abnormalities and amyloidosis.
    • The method's applicability to diverse sample types and amyloidosis classifications underscores its broad utility.