[Experimental study of the catatoxic effects of steroid hormones]

Tests set up on mice and rats brought evidence that spironolactone, progesterone, testosterone-propionate, methylandostendiol, desoxycorticosterone-acetate, methyltosterone, diethylstilbestrol, preparation PCN, megesterol-acetate and mestranol disply a catatoxic action, whose degree depends upon the method of evaluation and the animal species. A pattern for selection of catatoxic agents is proposed and some aspects of their mode of action are discussed.