[Pathological anatomy of the post-thrombophlebitic syndrome]

In the post-thrombophlebitis syndrome (PTPS) of the lower extremities pathomorphological changes develop in deep magistral venous trunks, communicating and surface veins, and microcirculation tracts. On the basis of the study on 90 cases of PTPS the following variants of morphological alterations in femoral veins as the most frequently affected segment in deep thrombophlebites were observed: complete restoration of the venous lumen but with the wall sclerosis muscle element atrophy, and loss of the valvular apparatus; partial restoration of the lumen on account of thrombus canalization; complete occlusion of the lumen on account of thrombosis and rethrombosis. Pathomorphological lesions of communicating ans surface veins and microcirculatory bed depend upon the features of lesions in magistral veins and result in the development of chronic venous insufficiency with the syndrome of regional capillary trophic changes leading to edema, dystrophic, necrobiotic, and sclerotic lesions.