[Cytogenetic studies following immune induction therapy]

This work deals with the question whether the immunisation with BCG-vaccine and leukemic cells leads to morphological changes of the chromosomes from children with acute leukemia. In respect of the small number of patients, and of the variant numbers in the single groups it is concluded, that immunological induction therapy is a possible gravitating factor in manifestation of isolate breaks and complex aberrations. It is not known whether one of them or both the components would be necessary, whether dosage and duration of vaccination have any influence, and how long after vaccination the gravitating influence may be seen.