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Alternans in human atrial monophasic action potenial
British Heart Journal
|November 1, 1977
Summary
This study reports a case of atrial tachycardia in a patient, revealing alternans during the action potential
Area of Science:
- Electrophysiology
- Cardiology
Background:
- Supraventricular tachycardia presents with rapid heart rate and absent P waves on ECG.
- Understanding the cellular mechanisms of tachycardia is crucial for effective treatment.
Observation:
- A patient with supraventricular tachycardia showed no visible P waves.
- Monophasic action potential recording revealed atrial tachycardia at 218/min.
- Alternans in phase 2 of repolarization was observed in the action potential.
Findings:
- The study identified atrial tachycardia with a rate of 218/min in a patient.
- Phase 2 repolarization alternans was detected at the cellular level.
- This phenomenon was observed in human cardiac tissue.
Implications:
- Alternans of action potential repolarization occurs in humans at the cellular level.
- This finding may inform the understanding and management of cardiac arrhythmias.
- Further research into cellular alternans in human hearts is warranted.