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Updated: Aug 14, 2026

Multiparametric Optical Mapping of the Langendorff-perfused Rabbit Heart
Published on: September 13, 2011
[Oxygen supply to isolated rabbit heart during its perfusion with eryhem and blood]
Coronary vessels of the isolated rabbit heart were perfused with eryhem--a solution containing 2.5--3.0 g% of hemoglobin and with the rabbit own blood diluted to the Hb content corresponding to such in eryhem. The oxygen capacity of eryhem as per 1 g of Hb constituted 72% only of the oxygen capacity of erythrocyte Hb. It was shown that eryhem was capable of uptake, transportation and of giving up oxygen. At the same time the myocardium perfused with eryhem was in worse conditions of oxygen supply than the muscle perfused with blood. The required level of oxygen uptake was reached with the increase of coronary blood supply and more complete utilization of blood oxygen reserves.
Coronary vessels of the isolated rabbit heart were perfused with eryhem--a solution containing 2.5--3.0 g% of hemoglobin and with the rabbit own blood diluted to the Hb content corresponding to such in eryhem. The oxygen capacity of eryhem as per 1 g of Hb constituted 72% only of the oxygen capacity of erythrocyte Hb. It was shown that eryhem was capable of uptake, transportation and of giving up oxygen. At the same time the myocardium perfused with eryhem was in worse conditions of oxygen supply than the muscle perfused with blood. The required level of oxygen uptake was reached with the increase of coronary blood supply and more complete utilization of blood oxygen reserves.

