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Hypertension due to Ask-Upmark kidney.

J D Sobel, N Hampel, A Kursbaum

    British Journal of Urology
    |November 1, 1977
    PubMed
    Summary
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    Surgical removal of a unilateral hypoplastic kidney, also known as an Ask-Upmark kidney, effectively cured severe hypertension in a young girl. This case highlights the Ask-Upmark kidney as a treatable cause of renovascular hypertension.

    Area of Science:

    • Nephrology
    • Cardiology
    • Pediatric Surgery

    Background:

    • Renovascular hypertension can stem from renal anomalies.
    • The Ask-Upmark kidney is a rare congenital kidney malformation.
    • Identifying surgical candidates is crucial for successful hypertension management.

    Observation:

    • A young female patient presented with severe hypertension.
    • The hypertension resolved completely following surgical nephrectomy.
    • The affected kidney was pathologically identified as an Ask-Upmark kidney.

    Findings:

    • Clinicopathological analysis confirmed the Ask-Upmark kidney diagnosis.
    • The etiology of hypertension was directly linked to the hypoplastic kidney.
    • No renin-angiotensin system abnormalities were detected, suggesting a non-RAAS mechanism.

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    Implications:

    • Surgical intervention for Ask-Upmark kidneys can be curative for severe hypertension.
    • This case underscores the importance of considering rare renal anomalies in pediatric hypertension.
    • Further research into the pathogenesis of hypertension in Ask-Upmark kidneys is warranted.