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Diet and heart: a postscript.

J N Morris, J W Marr, D G Clayton

    British Medical Journal
    |November 19, 1977
    PubMed
    Summary
    This summary is machine-generated.

    A study of 337 men found that higher energy intake and cereal fibre protected against coronary heart disease (CHD). This suggests dietary fibre from cereals may be beneficial for cardiovascular health.

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    Area of Science:

    • Nutritional Epidemiology
    • Cardiovascular Disease Research

    Background:

    • Coronary heart disease (CHD) remains a leading cause of mortality worldwide.
    • Dietary factors are known to influence cardiovascular health, but specific protective elements require further investigation.

    Purpose of the Study:

    • To investigate the relationship between dietary intake and the incidence of clinical coronary heart disease (CHD) in a cohort of middle-aged men.
    • To identify specific dietary components associated with a reduced risk of developing CHD.

    Main Methods:

    • A seven-day individual weighed dietary survey was conducted among 337 healthy middle-aged men in London and south-east England between 1956-1966.
    • Follow-up data was collected until 1976 to ascertain the incidence of clinical CHD.

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    Main Results:

    • A total of 45 cases of CHD were diagnosed during the follow-up period.
    • Men with higher energy intake exhibited a lower rate of CHD.
    • Independently, a high intake of dietary fibre from cereals was associated with a reduced incidence of CHD.
    • No association was found between CHD and the consumption of refined carbohydrates.
    • A trend towards fewer CHD cases was observed in men with a higher polyunsaturated to saturated fatty acid ratio, though not statistically significant.

    Conclusions:

    • Higher energy intake, potentially reflecting physical activity, and a diet rich in cereal fibre appear to be protective against the development of coronary heart disease.
    • The protective mechanism of cereal fibre warrants further investigation.
    • Dietary patterns, particularly cereal fibre consumption, may play a significant role in primary prevention of CHD.