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Related Experiment Videos

Desmoplastic trichoepithelioma.

M H Brownstein, L Shapiro

    Cancer
    |December 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Desmoplastic trichoepithelioma is a distinct skin tumor found on the face, predominantly in adult females. Histological examination is crucial for differentiating it from other similar skin neoplasms.

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    Area of Science:

    • Dermatopathology
    • Oncology

    Background:

    • A distinct clinicopathologic entity presenting as facial tumors was observed.
    • The entity occurred in 49 patients, with a median age of 46 years.

    Purpose of the Study:

    • To describe the clinicopathologic features of a distinctive entity.
    • To name this entity and differentiate it from other neoplasms.

    Main Methods:

    • Clinicopathologic analysis of 50 tumor examples from 49 patients.
    • Histological examination of tumor morphology.

    Main Results:

    • Tumors predominantly occurred on the face (98%), mainly the cheek, chin, and forehead.
    • 85% of affected patients were female; lesions were 3-8 mm, often annular with a raised border and central depression.

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  • Histology revealed basaloid cell strands and epidermoid cysts within a fibrotic stroma.

    • Conclusions:

    • The entity was named desmoplastic trichoepithelioma.
    • Histological differentiation from basal cell carcinoma, cutaneous metastasis, and adnexal neoplasms is necessary.