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Related Experiment Videos

Streptococcus milleri in the appendix.

P M Poole, G Wilson

    Journal of Clinical Pathology
    |October 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Streptococcus milleri is frequently found in inflamed appendices, suggesting it plays a role in appendicitis. This bacterium was also detected in other abdominal sites during appendicitis cases.

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    Area of Science:

    • Microbiology
    • Gastroenterology
    • Surgical Pathology

    Background:

    • The appendix's role in harboring bacteria is not fully understood.
    • Streptococcus milleri is a known opportunistic pathogen.

    Purpose of the Study:

    • To investigate the appendix as a potential habitat for Streptococcus milleri.
    • To compare the isolation rates of S. milleri in normal versus inflamed appendices.

    Main Methods:

    • Examination of both normal and inflamed appendix tissues.
    • Bacterial culture using enrichment broth with nalidixic acid and sulphadimidine.

    Main Results:

    • S. milleri was isolated from 25% of normal appendices and over 50% of inflamed appendices.

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  • A significant correlation was observed between S. milleri presence and purulent appendicitis.
  • S. milleri was also found in other abdominal sites associated with appendicitis.

    • Conclusions:

    • The appendix serves as a significant reservoir for Streptococcus milleri.
    • S. milleri is strongly associated with the development and purulent manifestations of appendicitis.