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Cerebrovascular incidents after myocardial infarction

P M McAllen, J Marshall

    Journal of Neurology, Neurosurgery, and Psychiatry
    |October 1, 1977
    PubMed

    Insights

    Survivors of myocardial infarction show a low prevalence of cerebrovascular disease, including stroke and transient ischemic attacks. This study confirms the low incidence, suggesting reduced cardiac dysrhythmia post-myocardial infarction may prevent embolism.

    Area of Science:

    • Cardiovascular Medicine
    • Neurology
    • Pathology

    Background:

    • Pathological studies reveal a strong link between atheroma in coronary, cerebral, and carotid arteries.
    • Myocardial infarction necropsy findings often show severe carotid artery atheroma.
    • Cerebral and carotid circulation obstructions are frequently caused by cardiac embolism.

    Purpose of the Study:

    • To investigate the prevalence of cerebrovascular disease in myocardial infarction survivors.
    • To determine if the low observed prevalence is due to underdiagnosis.
    • To assess clinical manifestations of cerebrovascular disease in this cohort.

    Main Methods:

    • A five-year follow-up study of 260 myocardial infarction survivors.
    • Detailed clinical assessment for cerebrovascular disease manifestations.
    • Analysis of stroke and transient cerebral ischemic attack incidence.

    Main Results:

    • Confirmed a surprisingly low prevalence of cerebrovascular disease in myocardial infarction survivors.
    • Reported a 4% prevalence of completed strokes.
    • Reported a 2% prevalence of transient cerebral ischemic attacks.

    Conclusions:

    • The low prevalence of cerebrovascular disease in myocardial infarction survivors is confirmed.
    • A potential explanation is the decreased frequency of cardiac dysrhythmia post-myocardial infarction, reducing embolism risk.
    • Further research may explore the mechanisms behind reduced dysrhythmia and embolism post-MI.

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