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Updated: Aug 11, 2026

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
Published on: September 27, 2012
Activity rhythms and adiurnal light-dark control
Abstract:
The running-wheel activity pattern of mature male rats was successfully synchronized to light-dark cycles as long as 48 hours and as short as 16 hours. Even after 6 months' exposure to "days" longer than the normal 24 hours, the animals returned promptly to circadian rhythmicity when placed under freerunning conditions of continuous dark. That such rhythms also reappeared when the light condition of the 36-hour cycle was reduced from 660 to 33 lumens per square meter suggests that brightness may be the critical factor in the unexpectedly broad range of entrainment demonstrated.
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