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Updated: Aug 18, 2026
06:11
Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
The therapeutic dilemma of carcinomas of unknown origin
Journal of Surgical Oncology
|January 1, 1977
Abstract:
The charts of 23 patients with metastatic carcinoma were reviewed retrospectively in hospitalized patients who had no apparent primary lesion. Eleven patients eventually had autopsies. The primary became apparent in 8 patients either pre- or post mortem. Treatment by operative intervention, and/or radiation therapy, and/or chemotherapy are discussed. The discussion reviews mechanisms of metastasis, problems in pathological interpretation, and considerations for evaluation of such patients.
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