Related Experiment Videos
The effect of apomorphine injection into caudate nucleus on electrical activity of some structures of the rabbit
Polish Journal of Pharmacology and Pharmacy
|September 1, 1977
Abstract:
The studies were carried out on rabbits with chronically implanted electrodes and cannulas. Apomorphine, dopamine, or haloperidol were injected into the caudate nucleus of wakeful rabbits at a volume of 2 microliter. EEG was recorded from gyrus cinguli anterior, nucleus dorsalis raphe, and dorsal part of hippocampal formation. Apomorhine produced a dose-dependent desynchronization of EEG in the structure tested. This effect did not appear when dopaminergic receptors were blocked by previous systemic (1.2 mg/kg) or intracaudal (10microgram) injection of heloperidol.