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[The effect of carbenoxolone on stress ulcers in rats]
Abstract:
By an immobilisation with a 72 hour's interruption of intake of fluid and nutrition stress ulcers were produced in the stomach of Wistar rats. Through a sound 34 animals received daily 25 mg/kg/body weight carbenoxolon. In them ulcers were found in nearly the same number as in the 30 controls. A conspicuous accumulation of ulcers in the pre-stomach or glandular stomach was not observed. A protective effect of the carbenoxolon could not be proved.