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Experiences with polyglactin 910 (Vicryl) in general surgery.

B Blomstedt, S I Jacobsson

Acta Chirurgica Scandinavica

|January 1, 1977

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Polyglactin 910 (Vicryl) sutures exhibit high tensile strength and no increased wound complications. This synthetic material shows promise as a replacement for catgut and non-absorbable sutures in general wound healing.

Area of Science:

Surgical Materials Science
Biomaterials Engineering
Wound Healing Research

Background:

Suture materials are crucial in surgical procedures, influencing wound healing and integrity.
Polyglactin 910 (Vicryl) is a synthetic absorbable suture with established clinical use.
Comparative analysis with natural and other synthetic sutures is essential for optimal material selection.

Purpose of the Study:

To evaluate the physical properties of polyglactin 910 (Vicryl) sutures.
To compare polyglactin 910 with other common suture materials.
To assess the clinical performance and safety of polyglactin 910 in surgical wound healing.

Main Methods:

Experimental testing of physical properties including fluid absorption, capillary action, tensile strength, and elongation at break.

Related Experiment Videos

Clinical evaluation of wound healing outcomes in patients undergoing laparotomy and inguinal hernia repair.

Assessment of wound infection rates and gastrointestinal anastomotic leakage.

Main Results:

Polyglactin 910 demonstrates high tensile strength, comparable or superior to non-absorbable synthetics.
The material exhibits high fluid absorption but low capillary action.
No increased wound infections, hernias, or anastomotic leaks were observed in clinical follow-up.

Conclusions:

Polyglactin 910 possesses favorable physical and clinical properties for wound closure.
It appears suitable for replacing both catgut and non-absorbable sutures in cases with expected normal wound healing.
The material demonstrates a good safety profile with minimal adverse wound reactions.