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Related Experiment Videos

Lingual thyroid: review, case reports, and therapeutic guidelines.

D J Weider, W Parker

    The Annals of Otology, Rhinology, and Laryngology
    |November 1, 1977
    PubMed
    Summary

    Lingual thyroid, a rare condition more common in females, involves thyroid tissue at the base of the tongue. Initial thyroid hormone replacement is recommended as the safest and most effective treatment.

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    Area of Science:

    • Endocrinology
    • Embryology
    • Otolaryngology

    Background:

    • Review of existing literature on lingual thyroid.
    • Discussion of thyroid gland embryology and development.
    • Exploration of potential roles of lateral thyroid primordia.

    Observation:

    • Lingual thyroid is rare, with a 4:1 to 5:1 female predominance.
    • Pathologic findings in lingual thyroid mimic cervical thyroid tissue, including goiter.
    • Diagnostic tools include mirror examination, iodine-125 scans, and tomography.

    Findings:

    • Thyroid function studies are crucial for assessing functional status.
    • Treatment options include surgery, radioactive iodine (I-131), and thyroid hormone replacement.
    • Surgical and radioactive iodine treatments often necessitate lifelong thyroid hormone supplementation.

    Implications:

    • Initial thyroid hormone replacement therapy is proposed as the primary treatment.
    • This approach is favored for its simplicity, safety, efficacy, and noninvasive nature.
    • Reports include four new cases, contributing to the understanding of this condition.

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