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Related Experiment Videos

Cardiac abnormality in polymyositis.

G P Sharratt, G Danta, P H Carson

    Annals of the Rheumatic Diseases
    |December 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Cardiac involvement is common in polymyositis patients, especially those with long-standing, severe disease. Simple noninvasive tests like systolic time intervals can detect left ventricular dysfunction in polymyositis.

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    Area of Science:

    • Cardiology
    • Neurology
    • Rheumatology

    Background:

    • Polymyositis is an idiopathic inflammatory myopathy characterized by symmetrical proximal muscle weakness.
    • Cardiac involvement in polymyositis is not well-characterized, necessitating further investigation.
    • Early detection of cardiac complications is crucial for patient management.

    Observation:

    • Thirteen patients diagnosed with polymyositis underwent comprehensive cardiac evaluation.
    • Clinical examination, chest x-ray, electrocardiogram (ECG), and systolic time intervals (STIs) were utilized.
    • Five out of thirteen patients exhibited clear evidence of cardiac involvement.

    Findings:

    • Patients with cardiac involvement presented with more long-standing, severe, and active polymyositis compared to those without.

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  • ECG findings frequently included arrhythmias and conduction disturbances.
  • Abnormal STIs, indicative of left ventricular dysfunction, were observed in 4 of the 5 affected patients.

    • Implications:

    • Left ventricular dysfunction is a more common complication of polymyositis than previously recognized.
    • Systolic time intervals offer a simple, noninvasive method for screening and detecting cardiac involvement in polymyositis.
    • These findings underscore the importance of cardiac monitoring in polymyositis patients.