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T1 bladder tumours.

J L Williams, J C Hammonds, N Saunders

British Journal of Urology

|January 1, 1977

Summary

This summary is machine-generated.

Transurethral resection or cystodiathermy effectively treats T1 bladder transitional cell tumors, with good survival rates. However, poor differentiation and high mitotic rates indicate a higher risk of invasive tumor development.

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Area of Science:

Uro-oncology
Surgical oncology
Pathology

Background:

Transitional cell tumors of the bladder are common.
T1 tumors invade the lamina propria.
Treatment options include transurethral resection and cystodiathermy.

Purpose of the Study:

To review outcomes of T1 bladder transitional cell tumors treated with transurethral resection or cystodiathermy.
To identify prognostic factors for tumor progression and survival.

Main Methods:

Retrospective review of 167 patients with T1 bladder transitional cell tumors.
Treatment modalities included transurethral resection or cystodiathermy.
Analysis of tumor characteristics and patient survival.

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Main Results:

Overall 3-year survival was 83.2%, and 5-year survival was 71.8%.
7.8% of patients developed invasive tumors.
Unfavorable prognostic factors included moderate/poor differentiation, high/moderate mitotic rate, and high/moderate pleomorphism.
Multiple tumors showed similar survival but higher rates of lamina propria invasion.

Conclusions:

Transurethral resection and cystodiathermy offer favorable survival for T1 bladder tumors.
Tumor differentiation, mitotic rate, and pleomorphism are critical prognostic indicators.
Careful monitoring is essential, especially for patients with unfavorable initial tumor characteristics.