Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

99Technetium bone scanning in experimental osteomyelitis.

L Risky, M L Goris, D J Schurman

    Clinical Orthopaedics and Related Research
    |October 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Cellular uptake of ribonuclease A-functionalised core-shell silica microspheres.

    Journal of materials chemistry. B·2020
    Same author

    Prophylactic antibiotics in orthopedic surgery.

    Orthopedics·2014
    Same author

    Three-dimensional quantitative analysis of scintigraphic tomographic images after elastic transformation to a template.

    Surgical technology international·2010
    Same author

    In vivo imaging of acute cardiac rejection in human patients using (99m)technetium labeled annexin V.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2002
    Same author

    Interhemispheric asymmetry of regional cerebral blood flow in prepubescent boys with attention deficit hyperactivity disorder.

    Nuclear medicine communications·2001
    Same author

    Measurement of perioperative flexion-extension mechanics of the knee joint.

    The Journal of arthroplasty·2001
    Same journal

    What Is the Effect of Robot Reduction in Displaced Pelvic Fractures? A Multicenter Randomized Clinical Trial.

    Clinical orthopaedics and related research·2026
    Same journal

    Radial Head Fractures Cluster in the Anterolateral and Anteromedial Quadrants and Do Not Correlate With Coronoid Fracture Types.

    Clinical orthopaedics and related research·2026
    Same journal

    Reduced Cerebellar Activation With Eyes Closed Is Associated With Delayed Peroneal Reaction Time in Patients With Chronic Ankle Instability.

    Clinical orthopaedics and related research·2026
    Same journal

    Are Social Determinants of Health Disparities Associated With Worse Completion Rates for Patient-reported Outcome Measures After Total Joint Arthroplasty?

    Clinical orthopaedics and related research·2026
    Same journal

    Are Age-based Cutoffs for THA Logically Consistent?

    Clinical orthopaedics and related research·2026
    Same journal

    Clinical Presentation Patterns and Outcomes of Decompression for Suprascapular Neuropathy: A Retrospective Surgical Series.

    Clinical orthopaedics and related research·2026
    See all related articles

    In experimental osteomyelitis, standard X-rays detected bone infection more reliably than bone scintigraphy. Further research is needed to explain scintigraphy findings in this rabbit model.

    Area of Science:

    • Orthopedics
    • Nuclear Medicine
    • Veterinary Pathology

    Background:

    • Osteomyelitis diagnosis often relies on imaging, but early detection can be challenging.
    • Experimental models are crucial for understanding bone infection dynamics.
    • The utility of bone scintigraphy versus radiography in early osteomyelitis requires clarification.

    Purpose of the Study:

    • To evaluate the diagnostic accuracy of bone scintigraphy and radiography in an experimental rabbit model of osteomyelitis.
    • To investigate the natural history of bone infection using these imaging modalities.

    Main Methods:

    • A rabbit model was established by injecting Staphylococcus aureus and a sclerosing agent into the tibial metaphysis.
    • Bone scintigraphy using 99m-Technetium phosphate compounds was performed at multiple time points.

    Related Experiment Videos

  • Radiography (roentgenograms) and pathological review were conducted.

    • Main Results:

    • Radiography demonstrated higher sensitivity (94%) in detecting osteomyelitis compared to bone scintigraphy (78%).
    • Early scintigraphic findings, including decreased uptake, did not reliably predict final results.
    • Pathological findings did not fully explain the observed scintigraphic patterns.

    Conclusions:

    • Standard radiography is more sensitive than bone scintigraphy for diagnosing experimental osteomyelitis in this rabbit model.
    • The physiological basis for scintigraphic findings in this model remains unclear.
    • Further investigation into bone blood flow and tissue-specific factors is warranted.