Selection of plastic containers for pharmaceuticals

With the awareness of the possibility of drug-plastic interaction, before substitution of a plastic container for glass, steps should be taken to ensure safety. This process is fraught with difficulties because of the complexity of plastic materials and even wider range of drug substances offered for sale in a variety of dosage forms. The selection of an appropriate container for pharmaceutical should be preceded by adequate testing to recognize the properties of the packaging material, and the stability, safety, and compatibility of the preparation packed in it. The same care and control used in the manufacture of a drug product should be used for the plastic packaging system.