[Antigenic structure of phytohemagglutinin-stimulated mouse lymphocytes using specific antisera]

The use of antiserum to the intact and the PHA-transformed lymphocytes showed that a new antigenic determinant (or determinants) appeared on the surface of lymphocytes after 68-hour PHA-stimulation. Intact lymphocytes or cells stimulated by the PHA for 2 hours only didn't carry this antigenic marker. At the same time the quantity (or density) of the antigenic markers present on the surface of the intact lymphocytes was lowered in the lymphocytes stimulated with the PHA for a long time.