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Progressive systemic sclerosis complicated by diffuse pulmonary haemorrhage.

J Kallenbach, I Prinsloo, S Zwi

    Thorax
    |December 1, 1977
    PubMed
    Summary
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    Progressive systemic sclerosis with pulmonary fibrosis can lead to diffuse pulmonary hemorrhage, causing recurrent bleeding. This rare association, a complication of scleroderma, eventually remitted with prednisone treatment.

    Area of Science:

    • Pulmonology
    • Rheumatology
    • Internal Medicine

    Background:

    • Progressive systemic sclerosis is a multisystem autoimmune disease characterized by fibrosis.
    • Pulmonary fibrosis is a common and serious complication of systemic sclerosis.

    Observation:

    • A rare case of progressive systemic sclerosis with pulmonary fibrosis presented with recurrent hemoptysis.
    • The hemoptysis was attributed to diffuse pulmonary hemorrhage, an unusual complication.

    Findings:

    • No prior reports were found documenting this specific association between systemic sclerosis, pulmonary fibrosis, and diffuse pulmonary hemorrhage.
    • The pulmonary hemorrhage eventually remitted following the initiation of daily prednisone treatment (40 mg).

    Implications:

    Related Experiment Videos

    • This case highlights a potentially life-threatening but treatable complication of systemic sclerosis.
    • Early recognition and treatment with corticosteroids may be beneficial in managing diffuse pulmonary hemorrhage in scleroderma patients.