[Morphological findings in the liver tissue of Australia antigen carriers]

In twenty-four blood-donors were performed, after the average period of seventy-four days following the evidence of HB Ag in blood, the punction biopsies of the hepatic tissue. In microscopical examination one finding corresponded with the picture of a moderate, chronically persisting hepatitis, and in the twenty-first sample we found non-characteristic alterations, especially in the form of matrix activation of Kupffer's cells and isolated, dispersing resorption histiocytary nodules. Demonstrated in ten blood-donors was HB Ag in the plasma of hepatocytes.