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[Electrolytic changes in thyrotoxicosis].

I Dinkov, M Minchev, I Nonchev

    Vutreshni Bolesti
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Thyrotoxicosis patients show normal serum sodium and slightly decreased potassium. Red blood cell changes include increased volume and decreased hemoglobin, correlating with disease severity.

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    Area of Science:

    • Endocrinology
    • Hematology
    • Clinical Biochemistry

    Background:

    • Thyrotoxicosis, a condition of excess thyroid hormones, can impact various physiological systems.
    • Understanding the hematological and electrolyte disturbances associated with thyrotoxicosis is crucial for patient management.

    Purpose of the Study:

    • To investigate serum electrolyte concentrations and red blood cell parameters in patients with thyrotoxicosis.
    • To correlate these parameters with the severity of thyrotoxicosis.

    Main Methods:

    • Serum electrolyte levels (sodium, chloride, potassium) were measured in 94 thyrotoxicosis patients and 40 healthy controls.
    • Hematocrit, mean erythrocyte volume, and mean hemoglobin concentration were analyzed.
    • Correlation analysis was performed between hematological parameters and disease severity.

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    Main Results:

    • Patients exhibited normal serum sodium levels, a slight increase in chloride, and a slight decrease in potassium.
    • Hematocrit levels decreased proportionally with increasing thyrotoxicosis severity.
    • An increase in average erythrocyte volume and a decrease in average hemoglobin concentration were observed.

    Conclusions:

    • Thyrotoxicosis is associated with specific alterations in serum electrolytes and red blood cell indices.
    • These hematological changes, including reduced hematocrit and altered red blood cell indices, appear to be linked to disease severity.