[Disorders of carbohydrate metabolism in severe fibrou-inflammatory pancreatic changes]

22 patients with bioptically found severe fibrou inflammatory changes of the pancreas underwent an after examination in order to exclude endocrine disturbances of the pancreas. The biopsy of the pancreas was carried out during an operation of the bile-duct. A restriction of the glucose tolerance was to be proved the more frequently the more distinct were the histological changes of the pancreas and the older were the patients. Post-operative increases of the fasting blood sugar appeared above all transitorily and rarely led to a manifestation of diabetes. It is recommended to exclude an endocrine functional disturbance of the pancreas not only when a typical symptomatology of pancreatitis is present, but also when there are possibly clinically not expected bioptical findings of a severe fibrous inflammatory change of the pancreas.