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Löffler's endocarditis and endomyocardial fibrosis--a nosologic entity?
Summary
Löffler's endocarditis and endomyocardial fibrosis may be part of a single disease spectrum. Eosinophilia in three Danish patients suggests eosinophilic granulocytes could be the cause of these cardiac conditions.
Area of Science:
- Cardiology
- Pathology
- Immunology
Background:
- Löffler's endocarditis and endomyocardial fibrosis are debated as separate entities or part of a disease spectrum.
- Endomyocardial fibrosis was historically considered exclusive to tropical regions.
- The role of eosinophils in these conditions is under investigation.