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Comparative medicine.

W I Gay

    Science (New York, N.Y.)
    |December 1, 1967
    PubMed
    Summary
    This summary is machine-generated.

    Researchers need better access to animal disease models for studying human conditions not easily replicated in labs. Compiling and publishing extensive lists and bibliographies of these models is crucial for advancing medical research.

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    Area of Science:

    • Comparative Medicine
    • Translational Research
    • Disease Modeling

    Background:

    • Many human diseases are difficult to study in laboratory settings or transmit to common animal models.
    • Existing knowledge on relevant animal disease models is fragmented and not readily accessible to researchers.
    • This gap hinders the development of new treatments and understanding of complex human pathologies.

    Purpose of the Study:

    • To address the need for accessible information on animal disease models for human health research.
    • To advocate for the compilation and dissemination of comprehensive resources on animal models.
    • To facilitate research on human diseases that lack suitable laboratory counterparts.

    Main Methods:

    • Reviewing existing literature and databases for documented animal disease models.

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  • Identifying specific conditions where animal models are particularly relevant but underutilized.
  • Proposing a framework for creating annotated bibliographies and extensive lists of these models.

    • Main Results:

    • The current availability of information on animal disease models is insufficient for many research needs.
    • A systematic compilation of animal disease models, annotated for specific human conditions, is feasible and necessary.
    • Such resources would significantly aid scientists in selecting appropriate models for their research.

    Conclusions:

    • Accessible and comprehensive lists and annotated bibliographies of animal disease models are essential for advancing human disease research.
    • Publication of these resources will bridge the gap between available animal models and the needs of scientists.
    • This initiative will accelerate the study of complex human diseases and the development of novel therapeutic strategies.