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Updated: Aug 19, 2026

11:42
Live-cell Imaging of Platelet Degranulation and Secretion Under Flow
Published on: July 10, 2017
A microanalytic study of particles transport across the alveoli: role of blood platelets
Abstract:
Following intratracheal injection of particles of colloidal gold (30 nm) in the rat, particles in the blood platelets of the alveolar capillaries can rapidly be observed. The presence of the gold is confirmed by microanalysis. The role of this phenomenon in pulmonary clearance is discussed.
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The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000 platelets, with...
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