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[Multiple nodular hyperplasia of liver associated with oral contraceptives (author's transl)]
Zentralblatt Fur Allgemeine Pathologie U. Pathologische Anatomie
|January 1, 1977
Abstract:
Two cases of multiple nodular hyperplasia of liver in patients with intake or oral contraceptives for several years are described. In one case the tumours appeared simultaneously, in the other case succesively. Macroscopically the nodular hyperplasia was misdiagnosed as metastasis. Microscopially the nodes presented an intense inflammatory infiltration of the septa, in one case with tuberculoid granulomas. The lesions showed a marked vascularity. Extremely dilated sinusoids could be seen in the needle biopsy of the macroscopically unchanged liver, a phenomenon occasionally seen in cases treated with oral contraceptives.
Keywords:
BiologyCase StudiesChlormadinone Acetate--side effectsContraceptionContraceptive Agents, Estrogen--side effectsContraceptive Agents, Female--side effectsContraceptive Agents, Progestin--side effectsContraceptive Agents--side effectsContraceptive Methods--side effectsEthinyl EstradiolFamily PlanningHepatic Effects--etiologyHistologyMestranol--side effectsNorethindroneNorethindrone AcetateOral Contraceptives, CombinedOral Contraceptives--side effectsPhysiologyResearch MethodologyStudies