Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antibiotic-associated pseudomembranous colitis.

W R Bartle, F G Saibil

    Canadian Medical Association Journal
    |January 22, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Efficacy of allopurinol in single daily dose.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Nontartrazine-containing drugs.

    Canadian Medical Association journal·2010
    Same author

    Seaweed, vitamin K, and warfarin.

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·2002
    Same author

    Grapefruit juice might still be factor in warfarin response.

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·1999
    Same author

    The effects of acetaminophen on pharmacokinetics and pharmacodynamics of warfarin.

    Journal of clinical pharmacology·1999
    Same author

    Diagnostic value of T cell reactivity in drug induced hepatitis.

    Gut·1999

    Two cases of pseudomembranous colitis were linked to ampicillin and trimethoprim-sulfamethoxazole. Both patients recovered with conservative management, highlighting antibiotic-associated colitis treatment.

    Area of Science:

    • Gastroenterology
    • Infectious Diseases
    • Pharmacology

    Background:

    • Antibiotic-associated colitis is a significant clinical concern.
    • Pseudomembranous colitis can manifest following antibiotic administration.
    • Specific antibiotics like ampicillin and trimethoprim-sulfamethoxazole have been implicated.

    Observation:

    • Two distinct cases of pseudomembranous colitis are presented.
    • Case 1 involved ampicillin; Case 2 involved ampicillin and trimethoprim-sulfamethoxazole.
    • Both patients exhibited symptoms including diarrhea, abdominal pain, and fever with elevated leukocytes.

    Findings:

    • Sigmoidoscopy and biopsy confirmed pseudomembranous colitis in both individuals.
    • The diagnosis was established through direct visualization and histological examination.

    Related Experiment Videos

  • Laboratory findings included leukocytosis, indicative of an inflammatory response.

    • Implications:

    • Conservative management strategies can be effective for antibiotic-associated pseudomembranous colitis.
    • Early diagnosis and appropriate supportive care are crucial for patient recovery.
    • Understanding antibiotic-specific risks informs clinical practice and patient counseling.