Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[ECG changes in an adverse reaction to dextran].

Wiener Medizinische Wochenschrift (1946)

|November 15, 1984

Summary

This summary is machine-generated.

A patient experienced a significant blood pressure drop after dextran 60 infusion during spinal anesthesia. This case highlights that ST segment elevation on ECG can occur in anaphylactoid shock reactions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

On the impact of surveillance test strategies: a cost-benefit modelling analysis based upon real-world data from SARS-CoV-2.

Public health·2024

Same author

<i>In vivo</i> / <i>in vitro</i> Correlation of Pharmacokinetics of Gentamicin, Vancomycin, Teicoplanin and Doripenem in a Bovine Blood Hemodialysis Model.

Frontiers in pharmacology·2021

Same author

Sepsis caused by multidrug-resistant klebsiella pneumoniae infection in a 23-year-old burn patient: case report and literature review.

Annals of burns and fire disasters·2018

Same author

Elimination of Doripenem during Dialysis and Pharmacokinetic Evaluation of Posthemodialysis Dosing for Patients Undergoing Intermittent Renal Replacement Therapy.

Antimicrobial agents and chemotherapy·2018

Same author

Micafungin Plasma Levels Are Not Affected by Continuous Renal Replacement Therapy: Experience in Critically Ill Patients.

Antimicrobial agents and chemotherapy·2017

Same author

Dalbavancin reduces biofilms of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE).

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2016

Area of Science:

Anesthesiology
Cardiology
Immunology

Background:

Dextran 60 infusion during spinal anesthesia can cause hemodynamic instability.
Anaphylactoid shock reactions are a rare but serious complication of dextran administration.
Electrocardiogram (ECG) changes can aid in diagnosing shock, but may be atypical.

Observation:

A 72-year-old patient developed a 30% drop in blood pressure with a constant pulse rate post-dextran 60 infusion.
Initial ECG showed ST segment elevation, atypical for anaphylactoid shock, leading to misdiagnosis.
Skin discoloration was a key indicator for correcting the diagnosis to anaphylactoid shock.

Findings:

The patient's condition improved within 10 minutes following therapy based on the "AAC-rule".

Related Experiment Videos

Complete recovery was achieved, demonstrating the effectiveness of timely intervention.

The case illustrates that ST segment elevation in ECG can be associated with anaphylactoid shock reactions.

Implications:

Clinicians should consider anaphylactoid shock in patients with hemodynamic instability after dextran infusion, even with atypical ECG findings.
Prompt recognition and management using established protocols (e.g., "AAC-rule") are crucial for patient recovery.
This case expands the understanding of potential ECG manifestations during anaphylactoid shock, emphasizing the importance of integrating clinical signs and symptoms for accurate diagnosis.