[Diagnostic difficulties in a case of visceral lupus with disseminated neurological signs]

The reported case was observed in a patient aged 54 years with disseminated lesions in the central nervous system. The history of the disease covered 18 years with periods of exacerbations and remissions. Seven years after the appearance of neurological signs involvement of the internal organs and skin was noted. In the serum antinuclear antibodies, LE cells and high gamma globulin level were demonstrated. The course of the disease and the observed immunological changes justify the diagnosis of the lupoid sclerosis form of visceral lupus erythematosus.