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[Anesthesia in surgery of Basedow's disease]
Summary
Preparing patients with Grave's disease for surgery is effective using anti-thyroid drugs, Lugol's solution, and propranolol. Plasmapheresis is a rare, effective treatment if this regimen fails, preventing thyroid storm.
Area of Science:
- Endocrinology
- Surgical Preparation
- Thyroid Disorders
Context:
- Grave's disease presents unique surgical preparation challenges.
- Standard pre-operative protocols involve anti-thyroid medications, Lugol's solution, and beta-blockers.
- Thyroid storm is a rare but serious complication.
Purpose:
- To evaluate the efficacy of a combined pre-operative regimen for Grave's disease.
- To assess the role of plasmapheresis in refractory cases.
- To report outcomes regarding thyroid storm incidence.
Summary:
- A combination of anti-thyroid medication, Lugol's solution, and propranolol effectively prepares Grave's disease patients for surgery.
- Plasmapheresis was utilized in rare instances where the standard treatment failed.
- No cases of thyroid storm were reported in 35 patients undergoing this preparation.
Impact:
- This multi-modal approach ensures adequate surgical preparation in Grave's disease.
- Plasmapheresis is identified as a potential treatment for thyroid storm if it occurs.
- The findings support a standardized, effective pre-surgical protocol for Grave's disease.