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Updated: Aug 17, 2026

Production of Replication-Defective Retrovirus by Transient Transfection of 293T cells
09:40

Production of Replication-Defective Retrovirus by Transient Transfection of 293T cells

Published on: December 4, 2007

[Isolation and characterization of retroviruses expressed in murine osteosarcomas induced by 90Sr]

J Merregaert, L Michiels, F S Pedersen

    Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales
    |January 1, 1984
    PubMed

    Insights

    Strontium-90 (90Sr) induces osteosarcomas in mice, linked to non-sarcomagenic viruses. However, the FBR murine osteosarcoma virus complex rapidly causes tumors and transforms cells, driven by a v-fos oncogene.

    Area of Science:

    • Oncology
    • Virology
    • Genetics

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