Related Experiment Video
Updated: Aug 8, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Cushing's disease in a patient with a 'nonfunctioning' pituitary tumor. Spontaneous development and remission
Abstract:
A 40-year-old woman had visual loss and a large nonfunctioning pituitary tumor. After partial surgical resection and radiation treatment, clinical and biochemical evidence of Cushing's disease developed. The pituitary source of her adrenocorticotropic hormone hypersecretion was documented on selective venous sampling. After 18 months of medical therapy with metyrapone and aminoglutethimide, the patient experienced a spontaneous remission of her hypercortisolism. A "nonfunctioning" pituitary tumor has a hypersecretory potential.
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