Related Experiment Videos
Connexon rearrangement in cardiac gap junctions: evidence for cytoskeletal control?
Cell and Tissue Research
|January 1, 1984
Abstract:
Using ultrarapid-freezing techniques and freeze-fracture electron microscopy, we report here a close association between cardiac gap junctions and specialized membrane domains containing regularly-spaced furrows. These specialized furrowed domains are observed only during periods of gap junction re-organisation (i.e., connexon redistribution) and may reflect the presence of underlying cytoskeletal elements controlling the position of connexons in the membrane.