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Obstructive jaundice caused by hepatocellular carcinoma.

R J Joehl, A B Abt

    Journal of Surgical Oncology
    |October 1, 1984
    PubMed
    Summary

    Hepatocellular carcinoma can cause obstructive jaundice. Early recognition of intrabiliary tumors is crucial for timely intervention in liver cancer patients.

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    Area of Science:

    • Hepatobiliary Surgery
    • Surgical Oncology
    • Gastroenterology

    Background:

    • Hepatocellular carcinoma (HCC) rarely presents with obstructive jaundice due to tumor invasion into the extrahepatic bile duct.
    • This complication is typically an autopsy finding, with ante mortem recognition being infrequent.

    Observation:

    • Two patients with hepatocellular carcinoma (HCC) initially presented with obstructive jaundice.
    • Operative removal of clotted blood and tumor from the common bile duct relieved the obstruction and allowed for biliary drainage.

    Findings:

    • The presence of blood clot and tumor debris in the common bile duct during surgery for obstructive jaundice suggests hepatocellular carcinoma.
    • Intrabiliary HCC causing obstruction and cholangitis should be considered in the differential diagnosis of jaundice and fever in HCC patients.

    Implications:

    • The association between obstructive jaundice and hepatocellular carcinoma may be more common than previously thought.
    • This highlights the importance of considering HCC in patients with unexplained obstructive jaundice.
    • Prompt surgical intervention can improve outcomes for patients with complicated HCC.

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