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Related Experiment Videos

Endorphins and exercise.

V J Harber, J R Sutton

    Sports Medicine (Auckland, N.Z.)
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Exercise significantly increases endogenous opioids, like beta-endorphin, impacting mood, pain perception, and hormonal responses. Their exact role in these physiological changes during exercise is still under investigation.

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    Area of Science:

    • Exercise physiology
    • Neuroendocrinology

    Background:

    • Endogenous opioids play a role in the body's response to exercise.
    • Opioid peptides, such as beta-endorphin, increase with exercise and training.

    Purpose of the Study:

    • To review evidence on exercise and endogenous opioids.
    • To examine the involvement of opioids in physiological processes during exercise.

    Main Methods:

    • Review of existing studies on exercise and endogenous opioids.
    • Use of opioid receptor antagonist naloxone to investigate opioid involvement.

    Main Results:

    • Serum concentrations of beta-endorphin and beta-lipotrophin increase with acute exercise and training.
    • Elevated beta-endorphin is linked to mood changes, altered pain perception, menstrual disturbances, and stress hormone responses.

    Related Experiment Videos

  • Potential role of endogenous opioids in ventilatory regulation and fatigue modulation during exercise.

    • Conclusions:

    • Endogenous opioids are significantly involved in the hormonal and metabolic response to exercise.
    • The precise mechanisms and sufficiency of peripheral endorphin changes in causing physiological effects remain unresolved.
    • Emerging evidence suggests a role for endogenous opioids in ventilatory control and fatigue perception during physical activity.